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Provides folic acid as methylfolate (5-MTHF) which is a stable and methylated form of folate. Methylfolate fulfils all the known uses of folic acid. Many supplements contain folic acid, however, folic acid has to undergo a number of steps within the body in order to be converted to the active form. If methylfolate supplementation is indicated, we recommend taking an all-round multi that includes all the B vitamins, including B12, as a foundation. This product could be taken in addition, if needed, on the advice of a health practitioner.
Methylfolate
One of the functions of folic acid is contributing to normal homocysteine metabolism. This is important as high homocysteine is a risk factor for chronic diseases including cardiovascular disease and cognitive decline
Folate is used in the methylation cycle – the purpose of this cycle, which occurs in all cells of the body, is to create S-adenosylmethionine (SAM), the universal methyl donor. SAM is used in many metabolic processes that require a methyl group
Folate contributes to normal:
- psychological function
- blood formation
- homocysteine metabolism
- maternal tissue growth during pregnancy
- immune system function
- amino acid synthesis
Folate contributes to the reduction of tiredness and fatigue
Folate has a role in the process of cell division
Supplemental folic acid intake increases maternal folate status. Low maternal folate status is a risk factor in the development of neural tube defects in the developing foetus. NB: we include methylfolate (i.e. folic acid) in our pregnancy multivitamin and mineral called Pregna-Plan at the government’s recommended dose for pregnancy of 400µg of folic acid per day.